PD Dr. rer. nat. Andreas Roos
Research Coordinator - Dep. of Neuropediatrics, University of Duisburg-Essen 🡵
Adjunct Professor - University of Ottawa 🡵
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GENOMIC AND PROTEOMIC SIGNATURES AS A GPS IN NEUROMUSCULAR DISEASES
Welcome dear visitor
As senior scientist I am working in the field of translational medicine with a main focus on neurodegenerative and neuromuscular disorders.
In order to understand the etiology of these diseases and to obtain a full picture, my work focusses on the identification of the genetic cause as well as on the discovery of the related pathophysiological consequences. For the latter purpose, various biochemical techniques including different proteomic approaches are applied by making use of in vitro and in vivo models as well as of patient-derived material.
I'd like to invite you to discover my field activity and related projects.
Best regards
Andreas Roos
News |  |
23.07.2021
Recently published paper
Expansion of the mutational spectrum of BMPER leading to diaphanospondylodysostosis and description of the associated disease process. Mol Genet Genomic Med. ~ Braun F, Gangfuß A, Stöbe P, Haack TB,... mehr
22.07.2021
Recently accepted paper
Muscular and molecular pathology associated with SPATA5-deficiency in a child with EHLMRS. International Journal of Molecular Science ~ Braun F*, Hentschel A, Sickmann A, Marteau T, Hertel S, Förster... mehr
02.05.2021
Recently published paper
Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex. Cells ~ Sicking M, Lang S, Bochen F, Roos A, Drenth J P H, Zakaria M, Zimmermann R, Linxweiler... mehr
01.05.2021
Recently accepted paper
Inflammation, fibrosis and skeletal muscle regeneration in LGMDR9 are orchestrated by macrophages. Neuropathology and Applied Neurobiology ~ Kölbel H, Preusse C, Brand L, van Moers A, Della marina A,... mehr
20.02.2021
Recently accepted paper
INPP5K- and SIL1-related disorders: identification of a common molecular pathway toward a treatment strategy. Brain. ~ Hathazi D, Cox D, D'Amico A, Tasca G, Charlton R, Carlier RY, Zahedi R, Kollipara... mehr
20.02.2021
Recently accepted paper
Exome reanalysis and proteomic profiling identified TRIP4 as a novel cause of cerebellar hypoplasia and spinal muscular atrophy (PCH1). European Journal of Human Genetics. ~ Töpf A, Pyle A, Griffin H,... mehr
03.07.2020
Interview mit Dr. Andreas Roos
Algorithmus vom INFORM DataLab verbessert Diagnose und Behandlung neuromuskulärer Erkrankungen. Link zum Interview mehr