Welcome
As a biologist by training I am working in the field of translational medicine with a main focus on neurodegenerative and neuromuscular disorders.
In order to understand the etiology of these diseases and to obtain a full picture, my work focusses on the identification of the genetic cause as well as on the discovery of the related pathophysiological consequences. For the latter purpose, various biochemical techniques including different proteomic approaches are applied by making use of in vitro and in vivo models as well as of patient-derived material.
News |  |
30.04.2019
Recently accepted paper
Proteomic Profiling Unravels a Key Role of Specific Macrophage Subtypes in Sporadic Inclusion Body Myositis ~ Roos A*, Preusse C*, Hathazi D, Goebel H-H, Stenzel W ~ Frontiers in Neurology ~ mehr
22.04.2019
Recently accepted paper
Identification of candidate protein markers in skeletal muscle of laminin-211-deficient CMD type 1A -patients ~ Kölbel H, Hathazi D, Jennings M, Horvath R, Roos A*, Schara U* ~ Frontiers in Neurology -... mehr
19.12.2018
Recently published paper
Neuromuscular Junction Changes in a Mouse Model of Charcot-Marie-Tooth Disease Type 4C ~ Cipriani S, Phan V, Médard Jean-Jacques, Horvath R, Lochmüller H, Chrast R, Roos A*, Spendiff S* ~ Int J Mol Sci.... mehr
20.11.2018
Recently published paper
SIL1 deficiency causes degenerative changes of peripheral nerves and neuromuscular junctions in fish, mice and human ~ Phan V, Cox D, Cipriani S, Spendiff S, Buchkremer S, O'Connor E, Horvath R, Goebel HH,... mehr