As a biologist by training I am working in the field of translational medicine with a main focus on neurodegenerative and neuromuscular disorders.
In order to understand the etiology of these diseases and to obtain a full picture, my work focusses on the identification of the genetic cause as well as on the discovery of the related pathophysiological consequences. For the latter purpose, various biochemical techniques including different proteomic approaches are applied by making use of in vitro and in vivo models as well as of patient-derived material.
Manuscript accepted for publication in JND
Sil1-Mutant Mice Elucidate Chaperone Function in Neurological Disorders Buchkremer S, González Coraspe JA, Weis J, Roos A mehr
Recently published paper
Proteome Profiling and Ultrastructural Characterization of the Human RCMH Cell Line: Myoblastic Properties and Suitability for Myopathological Studies Kollipara L, Buchkremer S, Weis J, Brauers E, Hoss M,... mehr